PRODUCT NAME: CHLORAMPHENICOL 99% TC
CHEMICAL FORMULA: C11H12Cl2N2O5
APPEARANCE: WHITE POWDER
CAS NO.: 56-75-7
Chloramphenicol is a broad spectrum antibiotic which inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step. Chloramphenicol is usually bacteriostatic and effective against a wide range of gram-positive and gram-negative organisms, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any indication in developed nations, although it is sometimes used topically for eye infections. Nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use. In low income countries, this medicine is still widely used because it is exceedingly inexpensive and readily available.
Chloramphenicol is used for the treatment of serious infections when microorganism is resistant to less toxic antibiotics and also when its ability to penetrate to the site of the infection is superior to less toxic alternative antibiotics. It’s forbidden to use this drug during pregnancy, lactation or known hypersensitivity.
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